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A discussion on imatinib and prostate cancer resistance

Let’s Talk: A Conversation with Dr. Charles Sawyers

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Let’s Talk

11 am EST -

September 17th, 2025

Don’t miss the Webcast

Understanding prostate cancer resistance is increasingly critical, as the disease remains a leading cause of cancer death in men and evolves through diverse mechanisms under therapeutic pressure. This has driven intense research into next-generation treatments, including PARP inhibitors, antibody-drug conjugates (ADCs), AR degraders, and combination immunotherapies.

Join us on September 17th - 11am EST

In our Webcast, Dr. Charles Sawyers and Mr. Christopher Ung will have an in-depth conversation on imatinib and prostate cancer resistance. The discussion will include the following topics:

  • History & development of imatinib

  • Applying lessons learned from imatinib

  • Life as a physician & researcher

  • From GIST to metastatic castration-resistant prostate cancer 

  • Future technology - TCEs, ADCs, TPDs

Dr. Charles Sawyers

Dr. Sawyers is an Howard Hughes Medical Institute investigator and serves as the Chair of the Human Oncology and Pathogenesis Program of the Memorial Sloan Kettering Cancer Center. He co-discovered the antiandrogen drug enzalutamide approved by the FDA in 2012 for treatment of advanced prostate cancer and shared the 2009 Lasker-DeBakery Clinical Medical Research Award for the development of the ABL kinase inhibitor imatinib.

Meet the Speakers

Mr. Christopher Ung

Mr. Christopher Ung has served in the companion diagnostics field since its inception and is one of the original pioneers of the personalized medicine field. He currently leads the development and execution of CellCarta’s strategic and business initiatives as Chief Scientific Business Officer.

Our Webcast series features in-depth conversations with thought leaders in precision therapeutics. Join our speakers as they engage in insightful fireside chat-style discussions on a variety of topics in this dynamic space.

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Dr. Charles Sawyers MD
Investigator, Howard Hughes Medical Institute


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